The extensive transgenerational transcriptomic effects of ocean acidification on the olfactory epithelium of the European seabass (dicentrarchus labrax) are associated with a better viral resistance

Progressive CO2-induced ocean acidification (OA) impacts marine life in ways that are difficult to predict but are likely to become exacerbated over generations. Here, we reasoned that longer-term exposure to OA would serve as a proxy for D. labrax acclimation to OA, and that a transcriptome analysis of the olfactory epithelium from F2 offspring would help us understand, at a molecular level, how fish acclimate over several years and across two successive generations. We also asked how OA-induced plastic responses impacts pathogen susceptibility by conducting an experimental betanodavirus challenge.